Abstract
The organocatalyzed asymmetric dearomative addition of phenols to indol-2-ones generated in situ from 3-bromooxindoles was reported. This methodology leads to the efficient construction of a series of enantioenriched 3,3′-disubstituted oxindoles bearing vicinal all-carbon quaternary stereocenters via a dearomatization process of phenols under mild reaction conditions. Additionally, the representative large-scale reactions and related transformations of the dearomatized products reveal the potential synthetic utility of this protocol.
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