Abstract
Added value: The conjugate addition of cyclic or acyclic α-substituted β-ketoesters to α,β-unsaturated ketones using a chiral organic catalyst (1) can be achieved with good enantioselectivity, diastereoselectivity, and yield. This asymmetric CC bond formation strategy provides a range of chiral building blocks 2 that contain an all-carbon quaternary stereocenter.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.