Construction of molecularly imprinted electrochemical sensor and penicillin detection based on FeS2@C

Abstract

This paper proposes for the first time a molecularly imprinted electrochemical sensor (MIECS) based on graphene-loaded FeS2@C modified glass electrode (GCE) for the efficient, rapid and sensitive detection of penicillin (PNC). Iron disulfide coated with biomass carbon has a very high specific surface area and volume effect, excellent electron transfer efficiency and conductivity, and is used to modify electrodes.In the experiment, electropolymerization was employed, with penicillin as the template molecule and o-phenylenediamine as the functional monomer, and the imprinted polymer membrane was successfully anchored on the surface of the FeS2@C composite material to specifically adsorb and detect penicillin. The materials were characterized by XRD, CV, DPV and other characterization methods. At the same time, CV and DPV were used to optimize the experimental conditions such as the molar ratio of functional monomer and template, elution time, resorption time, the number of polymerization cycles, and pH. In the end, it is concluded that under the experimental conditions of pH=3, molar ratio of 1:5, and polymerization circle number of 20, MIECS has good sensitivity, selectivity, reproducibility and stability to PNC.