Construction of highly efficient non-enzymatic glucose sensors based on micro-spherical Ni-metal-organic frameworks

Abstract

The Ni-metal-organic frameworks microspheres (Ni-BTC) were prepared and used directly to construct non-enzymatic glucose sensors. The Ni-BTC sensors displayed much higher glucose sensing performance than that of Ni-MOFs derived NiO, which showed wide detection regions of 5–3000[Formula: see text][Formula: see text]M and 3500–6000[Formula: see text][Formula: see text]M with the sensitivity of 932.68[Formula: see text][Formula: see text]A[Formula: see text]mM[Formula: see text]cm[Formula: see text] and 273.04[Formula: see text][Formula: see text]A[Formula: see text]mM[Formula: see text]cm[Formula: see text], respectively. Moreover, it also displayed good selectivity and favorable sensing feasibility for serum analysis. The high performance of the non-enzymatic glucose detection on Ni-BTC may be due to the highly efficient charge transfers during the electrocatalytic glucose oxidation process.