Year-end Sale % OFF 
Abstract
An iopanoate-selective electrode with a liquid membrane consisting of a tetraoctylammonium–iopanoate ion pair dissolved in p-nitrocumene is described. The electrode exhibits a rapid and slightly sub-Nernstian response (53 mV decade–1) to iopanoate concentrations ranging from 5 × 10–5 to 5 × 10–3 mol l–1 at pH 12 (0.01 mol l–1 NaOH). No serious interference from common ions and tablet excipients was found and the electrode was used for the direct assay of iopanoic acid tablets by means of the calibration graph technique. The results compared favourably with those given by the United States Pharmacopeia (USP) XXII titrimetric method which requires extraction of the drug with hot alcohol. The electrode was also used to study the complexation of iopanoate to β-cyclodextrin.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
