Abstract
Purpose: Pain is the principal symptom of knee osteoarthritis (OA), with approximately three quarters of OA patients experiencing constant pain. Amongst the pathological bony abnormalities in knee OA, subchondral bone marrow lesions (BMLs) are cardinal. The lesion-symptom discordance is a long-standing observation as about 50% of patients with structural OA radiographic features are asymptomatic. To date, topographical data is not fully utilised in the widely used radiographic scales and classification systems.
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