Abstract

Tongue examination is an important diagnostic method for judging pathological conditions in Kampo (traditional Japanese medicine), but it is not easy for beginners to learn the diagnostic technique. One reason is that there are few objective diagnostic criteria for tongue examination findings, and the educational method for tongue examination is not standardized in Japan, warranting the need for a tongue image database for e-learning systems that could dramatically improve the efficiency of education. Therefore, we constructed a database comprising tongue images whose findings were determined on the basis of votes given by five Kampo medicine specialists (KMSs) and confirmed the educational usefulness of the database for tongue diagnosis e-learning systems. The study was conducted in the following five steps: development of a tongue imaging collection system, collection of tongue images, evaluation and annotation of tongue images, development of a tongue diagnosis e-learning system, and verification of the educational usefulness of this system. Five KMSs evaluated the tongue images obtained from 125 participants in the following eight aspects: (i) tongue body size, (ii) tongue body color, (iii) tongue body dryness and wetness, (iv) tooth marks on the edge of the tongue, (v) cracks on the surface of the tongue, (vi) thickness of tongue coating, (vii) color of tongue coating, and (viii) dryness and wetness of tongue coating. Medical students (MSs) were given a tongue diagnosis test using an e-learning system after a lecture on tongue diagnosis. The cumulative and individual match rates (%) (individual match rates of 100% (5/5), 80% (4/5), and 60% (3/5) are shown in parentheses, respectively) were as follows: (i) tongue body size: 92.8 (26.4/26.4/40.0); (ii) tongue body color: 83.2 (10.4/20.8/52.0); (iii) tongue body dryness and wetness: 88.8 (13.6/34.4/40.8); (iv) tooth marks on the edge of the tongue: 88.8 (6.4/35.2/47.2); (v) cracks on the surface of the tongue: 96.8 (24.0/35.2/37.6); (vi) thickness of tongue coating: 84.8 (7.2/21.6/56.0); (vii) color of tongue coating: 88.0 (15.2/37.6/35.2); and (viii) dryness and wetness of tongue coating: 74.4 (4.8/19.2/50.4). The test showed that the tongue diagnosis ability of MSs who attended a lecture on tongue diagnosis was almost the same as that of KMSs. We successfully constructed a tongue image database standardized for training specialists on tongue diagnosis and confirmed the educational usefulness of the e-learning system using a database. This database will contribute to the standardization and popularization of Kampo education.

Highlights

  • Since tongue findings reflect a variety of systemic disorders, including malnutrition, tongue examination is one of the basic physical examinations

  • We have proposed an objective method determined by a majority vote to ensure the reliability of the diagnostic information of the tongue images used in the database

  • The aims of this study were to construct a database of tongue images, which are annotated with correct labels by Kampo medicine specialists (KMS), and to create a tongue diagnosis e-learning system using the database and verify its educational usefulness

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Summary

Introduction

Since tongue findings reflect a variety of systemic disorders, including malnutrition, tongue examination is one of the basic physical examinations. Atrophic glossitis, lichen planus, leukoplakia, hairy tongue, and glossodynia are sometimes associated with tongue disorders. Morphological abnormalities, including geographic tongue, fissured tongue, and macroglossia, are often observed [1,2,3]. These are associated with various pathological conditions, including malnutrition, infectious diseases, systemic diseases, hereditary diseases, age-related changes, and unknown causes [1,2,3]. Atrophic glossitis is associated with malnutrition [4] and is accompanied by a smooth red tongue surface with atrophy of the tongue papilla. Suppression of tongue papilla cell regeneration is caused by insufficient intake or malabsorption of specific nutrients such as iron (Plummer-Vinson syndrome due to iron deficiency anemia) [5], vitamin B12 (pernicious anemia) [6], vitamin B2, and folic acid [7]

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