Construction of a sensitive electrochemical sensor based on hybrid 1 T/2H MoS2 nanoflowers anchoring on rGO nanosheets for the voltammetric determination of acetaminophen

Abstract

In this work, an ultrasensitive electrochemical sensor towards quantitative detection of acetaminophen (AP) based on hybrid of metallic 1 T and semiconductive 2H phase molybdenum disulfide (1 T/2H MoS2) anchored on rGO sensing platform was constructed. The XRD, FESEM, FETEM and XPS analysis indicates that nanoflowers 1 T/2H MoS2 with walnut-like fold structure were in-situ loaded onto the surface of rGO nanosheets by the hydrothermal approach. The formation of stabilized 1 T MoS2 is associated with the influence of GO. The electrochemical tests of CV, EIS and DPV show that the hybrid composite MoS2/rGO remarkably promoted the detecting performance owing to the increased conductivity of 1 T MoS2 that can facilitate charge transfer kinetics, the great active sites on both basal and edge of planes of 1 T/2H MoS2 and the synergic effect of 1 T/2H MoS2 and rGO. After the test condition optimization, MoS2/rGO/GCE sensor has great electrocatalytic activity towards AP with wide linear range of 0.005–300 μM and low limit of detection of 1.7 nM (S/N = 3). Furthermore, the sensor shows excellent stability, repeatability, reproducibility and anti-interference performance. All results proved that the GO-assisted hydrothermal prepared hybrid 1 T/2H MoS2/rGO is promising material for electrochemical analysis.