Constructing densely functionalized Hajos–Parrish-type ketones with six contiguous stereogenic centers and two quaternary carbons in a formal [2 + 2 + 2] cycloaddition cascade

Abstract

Efficient construction of Hajos–Parrish-type ketones with six contiguous stereogenic centers in a formal [2 + 2 + 2] cycloaddition cascade. The spontaneous resolution of racemic product without the need for chiral agent has been achieved.