Abstract
Apoptosis is a physiological response in development and homeostasis of metazoans. Apoptosis is triggered during pathological events as a means to renew affected tissues and eliminate cancer cells. The immune system regulates the extrinsic pathway of apoptosis, where signals such as TNF? or displayed ligands on the surface of immune cells trigger signal cascades by death receptors present on targeted cells. Therapeutics, like Doxorubicin, lead to apoptosis successfully
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