Abstract
Abstract The construction of cage-type hydrocarbon scaffolds, potential bioisosteres for benzene, often involves multiple steps, making their selective syntheses challenging. However, by employing a scaffold editing technique that leverages the isomerization of the highly symmetrical cubane as a precursor, these can be synthesized more efficiently with fewer steps. In this study, we present a method for the selective synthesis of semibullvalene-1,3-dicarboxylic acid with a good yield, starting from dimethyl cubane-1,4-dicarboxylate, using a reaction in hot water.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
