Abstract

The aerial parts of Sideritis syriaca ssp . syriaca (Lamiaceae ) were extracted, after defatting, with diethyl ether, ethyl acetate and n-butanol. The antioxidant activities of the extracts were evaluated through in vitro model systems, such as 1,1-diphenyl-2-picryl hydrazyl (DPPH) and Co(II) EDTA-induced luminol chemiluminescence. In both model systems the ethyl acetate extract was the most effective. Phytochemical analysis of ethyl acetate extract showed the presence of two new isomeric compounds ( 1 and 1′), identified as 1-rhamnosyl, 1-coumaroyl, dihydrocaffeoyl, protocatechuic tetraester of quinic acid, as well as chlorogenic acid ( 2), apigenin 7-O-glucoside ( 3), apigenin ( 4), 4′-O-methylisoscutellarein 7-O-[6′′′-O-acetyl-β-D-allopyranosyl-(1 → 2)-β- d-glucopyranoside] ( 5), isoscutellarein 7-O-[6′′′-O-acetyl-β-D-allopyranosyl-(1 → 2)-β- d-glucopyranoside] ( 6), 4′-O-methylisoscutellarein 7-O[β- d-allopyranosyl-(1 → 2)-β- d-glucopyranoside] ( 7) and 4′-O-methylisoscutellarein 7-O-[β- d-allopyranosyl-(1 → 2)-6′′-O-acetyl-β- d-glucopyranoside] ( 8). The above compounds were identified by spectroscopic methods.

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