Consistency between computed tomographic enterography and enteroscopy in the detection of small intestinal Crohn's disease

Abstract

Objective To evaluate the diagnostic value of computed tomographic enterography (CTE) in the detection of small intestinal Crohn's disease (CD) with balloon-assisted enterography (BAE) as the reference standard.Methods The CTE and BAE data of 81 patients with CD were retrospectively analyzed.The small intestine of CD patients was divided into four segments,such as duodenum,jejunum,proximal ileum and distal ileum.With results of BAE as the reference standard,the sensitivity and specificity of CTE image (bowel wall thickening,mucosa enhancement,comb sign and extraenteric manifestations) in the detection of small intestinal CD were analyzed.Results A total of 182 small bowel segments were included,among which 14 segments were duodenum,17 were jejunum,75 were proximal ileum,and 76 were distal ileum.Among the CTE signs,the sensitivity and specificity of both bowel wall thickening over 3 mm and mucosa enhancement in the detection of small intestinal CD was 82.8％ and 74.2％,respectively.The sensitivity and specificity of bowel wall thickening over 5 mm in the detection of small intestinal CD was 68.1 ％ and 84.8％,respectively.The sensitivity and specificity of comb sign in the detection of small intestinal CD was 67.0％ and 82.1 ％,respectively.The sensitivity and specificity of extraenteric manifestations in the detection of small intestinal CD was 30.2％ and 97.0％,respectively.The sensitivity and specificity of bowel wall thickening over 3 mm in the detection of severe small intestinal inflammation was 89.0％ and 57.8％,respectively.Conclusions CTE has high sensitivity and specificity in detecting small intestinal CD and has good consistency with the results of BAE.CTE has certain reference value in the diagnosis of small intestinal CD. Key words: Crohn's disease; Balloon assisted enterography; Tomography