Consistencies of 3D TTE global longitudinal strain of both ventricles between assessors were worse for 2D, but better for 3D ventricular EF

Abstract

PurposeWe evaluated the consistency of different-assessors in estimating three-dimensional (3D) global-longitudinal-strain (GLS) of left (LV) and right ventricle (RV) using transthoracic-echocardiography (TTE) for LV and RV systolic-function. We compared results from two-independent-specialists using this-approach for 3D LV and RV parameters in a population with 74% hypertrophic-cardiomyopathy (HCM) patients. Methods58 patients (43 HCM (32 male; 62±15years) and 15 controls (5 male; 53±22years)) underwent TTE (Vivid-E9) to measure 2D and 3D GLS of the LV and RV by two-independent-specialists. ResultsConsistencies of estimates of 3D LV end-diastolic volume (EDV), end-systolic volume (ESV), and ejection-fraction (EF) between the two-assessors were 0.872 (3D LVEDV, P<0.001), 0.797 (3D LVESV, P<0.001), and 0.215 (3D LVEF, P=0.105). Consistencies of 2D and 3D LV GLS between two-assessors were 0.900 (2D LVGLS, P<0.001) and 0.874 (3D LVGLS, P<0.001). Consistencies of estimates of 3D RVEDV, RVESV, and RVEF between two assessors were 0.781 (3D RVEDV, P<0.001), 0.755 (3D RVESV, P<0.001), and 0.26 (3D RVEF, P=0.049). Consistencies of 2D and 3D GLS of whole RV and those of RV free wall only between two-assessors were 0.886 (2D GLS of whole RV, P<0.001), 0.687 (3D GLS of whole RV, P<0.001), 0.707 (2D GLS of RV free wall, P<0.001), and 0.630 (3D GLS of RV free wall, P<0.001). ConclusionsConsistencies of independent-estimates of 3D GLS of the LV and RV using TTE between two-assessors were worse than for 2D GLS of the LV and RV, but better than for 3D LVEF and RVEF in a population with 74% HCM patients.