Abstract
The advancement of guided bone regeneration (GBR), which restores various types of bone defects faster andmore safely, broadens the implant indications and opens up many possibilities. However, planning sufficientregeneration in severe vertical and horizontal bone defects, especially in periodontally compromised patients, is not easy. For the successful guided bone regeneration procedure, the clinician must carefully analyze the form of bone destruction in three dimensions and strictly select the appropriate membrane and bone graft material accordingly. In addition, key factors for GBR success such as blood supply, graft material and membrane stability,and primary closure should always be considered. Soft-tissue management and optimized flap design, various membrane fixation techniques seem to be another important factor for long-term success.
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