Abstract
Recent research has revealed the emergence of common themes in the molecular mechanisms of virulence in bacterial pathogens of plants and animals. In particular, the systems used for the global control of virulence factor synthesis and for the secretion of virulence determinants in diverse bacterial pathogens show strong conservation, implying evolutionary relatedness. Global control of virulence factor synthesis can be affected by a variety of environmental factors, bacterial ‘hormones’ and programmed genetic rearrangements.
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