Abstract
Objective To analyze the distribution of high conserved CTAG sequence in S.typhimurium DT104 and four insertions, then discuss the evolutionary relationship to provide the efficient clue for our research. Methods Tabulate the position and content of CTAG in four insertions of S.typhimurium DT104, and summarize its function and distribution in all Salmonella strains to explore the evolutionary relationship at 3 levels. Results The CTAG sequence eliminated from insertion is a progressive process from ends to the middle. The content and distribution of CTAG can provide the information of the insertions for the comparison of the evolutionary relationships. Conclusion High conserved CTAG sequence was dropped off during the development of Salmonella. The high conserved CTAG profiling can be considered as an efficient method to identify sequences for biological characterization. The insertion with the sequence can be deemed to be anindicter for the exploration of the relative evolutionary time relationship as well. Key words: Salmonella; CTAG; insertion; genome evolution
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