Abstract
The calcifying odontogenic cyst (COC) was first defined as a separate entity by Gorlin et al in 1962. 1 Gorlin R.J. Pindborg J.J. Clausen F.P. et al. The calcifying odontogenic cyst—A possible analogue of the cutaneous calcifying epithelioma of Malherbe An analysis of fifteen cases. Oral Surg. 1962; 15: 1235 Abstract Full Text PDF Scopus (269) Google Scholar The COC represents about 1% of jaw cysts, and although it may occur in soft tissue, it is most commonly found within bone. 2 Odell E.W. Morgan P.R. Biopsy Pathology of the Oral Tissues. Chapman and Hall Medical, London, UK1998 Google Scholar , 3 Shamaskin R.G. Svirsky J.A. Kaugards G.E. Intraosseous and extraosseous calcifying odontogenic cyst (Gorlin Cyst). J Oral Maxillofac Surg. 1989; 47: 562 Abstract Full Text PDF PubMed Scopus (42) Google Scholar Both the intraosseous and extraosseous forms occur with about equal frequency in the maxilla and mandible, mainly in the incisor and canine areas. 4 Altini M. Ferman A.G. The calcifying odontogenic cyst: Eight new cases and review of the literature. Oral Surg Oral Pathol Oral Radiol. 1975; 40: 751 PubMed Google Scholar , 5 Freedman P.D. Lumerman H. Gee J.K. Calcifying odontogenic cyst: A review and analysis of seventy cases. Oral Surg Oral Med Oral Pathol. 1975; 40: 93 Abstract Full Text PDF PubMed Scopus (110) Google Scholar , 6 Nagao T. Nakajima T. Fukushima M. et al. Calcifying odontogenic cyst: A survey of 23 cases in the Japanese literature. J Maxillofac Surg. 1983; 11: 174 Abstract Full Text PDF PubMed Scopus (36) Google Scholar , 7 Buchner A. The central (intraosseous) calcifying odontogenic cyst: An analysis of 215 cases. J Oral Maxillofac Surg. 1991; 49: 330 Abstract Full Text PDF PubMed Scopus (155) Google Scholar Although the peripheral COC affects individuals in the sixth decade of life, the central variant is observed most commonly in the second decade and does not show gender predilection. 7 Buchner A. The central (intraosseous) calcifying odontogenic cyst: An analysis of 215 cases. J Oral Maxillofac Surg. 1991; 49: 330 Abstract Full Text PDF PubMed Scopus (155) Google Scholar , 8 Buchner A. Merrell P.W. Carpenter W.M. et al. Central (intraosseous) calcifying odontogenic cyst. Int J Oral Maxillofac Surg. 1990; 19: 260 Abstract Full Text PDF PubMed Scopus (24) Google Scholar
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