Abstract

Background: Single-twin intrauterine death in the second and third trimesters poses a great concern and psychological stress to both the parents and the obstetrician. A multidisciplinary approach to conservative management is associated with improved perinatal outcome for the surviving twin. Case: We present a 30-year-old gravida 2 para 1 (1 alive). She had an emergency caesarean section during her first delivery. Having been referred from a military hospital, she presented at 22 weeks with single-twin intrauterine death. She was admitted and discharged after one week. Subsequently, she was managed conservatively and had weekly antenatal follow-up visits. She kept a daily fetal kick chart, had fortnightly ultrasound scans for fetal growth and wellbeing and weekly maternal clotting profile. At 37 weeks of gestation, she had a successful repeat caesarean delivery of a live, male neonate with a birth weight of 3.9kg and Apgar scores of 9 at one minute and 10 at five minutes. The remains of the dead co-twin (fetus papyraceus) were seen attached to the placenta. Follow-up by the neonatologist showed that his developmental milestones were normal and comparable to those of his singleton peers. Conclusion: The management of single-twin intrauterine death after the second trimester is psychologically tasking, requiring adequate counselling for the couple. The multidisciplinary approach, adopted in this study, improved perinatal outcome for the surviving co-twin after 15 weeks of conservative management. Prolonged paediatric follow-up of the survivor was imperative.

Highlights

  • Pregnancies with twins are high risk when compared with singleton pregnancies in terms of increased perinatal mortality, and have a high risk of single intrauterine death (SIUD), complicating up to 6% of twin pregnancies after the second trimester [1,2,3,4]

  • Fetal demise occurring after mid gestation (17 weeks gestation) may increase the risk of intrauterine growth restriction (IUGR), preterm labour, preeclampsia, and perinatal mortality in the surviving twin [8]

  • It may increase the risk of neurological complication in the surviving twin and is a cause of great concern and psychological stress to both parents and the obstetrician

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Summary

Introduction and Literature Review

Pregnancies with twins are high risk when compared with singleton pregnancies in terms of increased perinatal mortality, and have a high risk of single intrauterine death (SIUD), complicating up to 6% of twin pregnancies after the second trimester [1,2,3,4]. Fetal demise occurring after mid gestation (17 weeks gestation) may increase the risk of intrauterine growth restriction (IUGR), preterm labour, preeclampsia, and perinatal mortality in the surviving twin [8] It may increase the risk of neurological complication in the surviving twin and is a cause of great concern and psychological stress to both parents and the obstetrician. States that vascular anastomoses (frequently present in monochorionic placentas) allow shunting of blood from the surviving twin to the dead co-twin giving rise to periods of hypoperfusion, hypotension, anaemia and multiorganischaemia and neurological damage in the surviving twin In dichorionic pregnancy, these vascular anastomoses are not present, but the intrauterine environment that may have caused the initial fetal demise (infection, maternal medical disease) may place the surviving twin at risk as well. These should be performed along with fetal kick chart and regular maternal coagulation profile

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Case Report
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