CONSERVATIVE MANAGEMENT OF CENTRAL GIANT CELL LESION OF THE JAW: A CASE REPORT

Abstract

Central giant cell lesion (CGCL) is an intra-osseous benign lesion composed of ovoid or spindle-shaped mononuclear cells interspersed by multinucleated giant cells in a high vascularized connective tissue stroma. CGCL is prevalent in the first and second decades of life. The clinical behavior may be indolent or extensively osteolytic. In this report we present a case of successful treatment using intralesional injections of corticosteroids. A 9-year-old boy presented with an extensive asymptomatic swelling in the right maxilla. Computed tomography showed an expansive, well-circumscribed, multiloculated, hypodense lesion in the right maxilla, maxillary sinus, and nasal cavity. The incisional biopsy confirmed the diagnosis of CGCL; 0.4 mL of triamcinolone hexacetonide 20 mg/mL diluted in 0.6 mL of 2% lidocaine (epinephrine 1:100.000) was administered on a weekly basis for 14 weeks. One year later, no tumor was observed, which was confirmed by a fine-needle aspiration biopsy. No recurrence was observed in 7 years’ of follow-up.