Abstract
Different types of post-transcriptional transgene-induced gene silencing have been shown to occur in Neurospora (quelling) and plants (co-suppression). Common mechanistic features include triggering by duplicated coding sequences, simultaneous silencing of the transgene and endogenous genes, reversibility of silencing and post-transcriptional reduction of gene-specific mRNA. These shared features suggest that this type of gene silencing may have evolved from a common ancestral mechanism designed to protect genome integrity. Understanding the mechanisms involved may be particularly useful in biotechnological applications aimed at enhancing or avoiding gene silencing in transgenic plants and fungi.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
