Abstract

全球结直肠癌每年新发病例数约120万,年病死人数超过60万,发病率居第3位,病死率居第4位[1].近些年,结直肠癌的发病率呈明显上升趋势[1].因此,结直肠癌的治疗一直是国内外学者研究的热点.随着靶向治疗药物表皮生长因子受体(EGFR)抑制剂西妥昔单抗(Cetuximab)和帕尼单抗(Panitumumab)的问世,结直肠癌的治疗进入了靶向治疗时代。

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