Abstract

Digital mobility assessment using wearable sensor systems has the potential to capture walking performance in a patient's natural environment. It enables monitoring of health status and disease progression and evaluation of interventions in real-world situations. In contrast to laboratory settings, real-world walking occurs in non-conventional environments and under unconstrained and uncontrolled conditions. Despite the general understanding, there is a lack of agreed definitions about what constitutes real-world walking, impeding the comparison and interpretation of the acquired data across systems and studies. The goal of this study was to obtain expert-based consensus on specific aspects of real-world walking and to provide respective definitions in a common terminological framework. An adapted Delphi method was used to obtain agreed definitions related to real-world walking. In an online survey, 162 participants from a panel of academic, clinical and industrial experts with experience in the field of gait analysis were asked for agreement on previously specified definitions. Descriptive statistics was used to evaluate whether consent (> 75% agreement as defined a priori) was reached. Of 162 experts invited to participate, 51 completed all rounds (31.5% response rate). We obtained consensus on all definitions ("Walking" > 90%, "Purposeful" > 75%, "Real-world" > 90%, "Walking bout" > 80%, "Walking speed" > 75%, "Turning" > 90% agreement) after two rounds. The identification of a consented set of real-world walking definitions has important implications for the development of assessment and analysis protocols, as well as for the reporting and comparison of digital mobility outcomes across studies and systems. The definitions will serve as a common framework for implementing digital and mobile technologies for gait assessment and are an important link for the transition from supervised to unsupervised gait assessment.

Highlights

  • Mobility, or gait, can be influenced by a variety of chronic health conditions, spanning from neurological, respiratory, and cardiac to musculoskeletal disorders

  • Measures development to identify and agree upon a framework of narrative definitions for the assessment of digital mobility outcomes (DMOs) acquired in real-world conditions

  • The use of walking aids has been included into the definition as they may be an essential requirement for safe locomotion of people with gait impairments

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Summary

Introduction

Gait, can be influenced by a variety of chronic health conditions, spanning from neurological, respiratory, and cardiac to musculoskeletal disorders. Such conditions may include multiple sclerosis (MS), Parkinson’s disease (PD), chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), or proximal femoral fracture (PFF) [1,2,3,4,5,6]. The use of digital mobility outcomes (DMOs), which we refer to as digital measures acquired using digital health technology [15] has already been studied in clinical settings using brief, standardized tests in a range of diseases [2, 4, 16, 17]. DMOs quantified from real-world data are able to discriminate and detect gait impairments in various diseases [20, 23,24,25,26], accepted and routinely used tools are not applied in practice yet [27]

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