Consecutive primary carcinomas of bronchus and larynx.

Abstract

THE PHENOMENON OF primary carcinomas occurring simultaneously or consecutively in two or more organs is encountered not uncommonly in modern oncologic literature. However, an autopsy series of 234 multiple primary malignant neoplasms performed from 1926 to 1944 and reported by Warren and co-workers in 1932¹and 1944²contained only a single instance of primary carcinoma of bronchus and larynx in the same patient. In a series of 113 patients with multiple primary malignant neoplasms who were treated surgically at the Mayo Clinic in 1937 and reported by Stalker and co-workers,³there was not a single primary carcinoma of bronchus and larynx in the same patient. In 1955 Cahan⁴reported 19 instances of this combination of primary neoplasms among 81 cases of multiple primary carcinomas which were collected over a period of 28 yr at the Memorial Center for Cancer and Allied Diseases. A recent published report