Abstract
Pyridoxine HCl plays an important role in the human body as a coenzyme in the synthesis process of amino acids and neurotransmitters such as serotonin, norepinephrine, aminolevulinic acid, sphingolipids, etc. The objective of this study was to determine the effect of the Trivedi Effect®-Consciousness Energy Healing Treatment on the various physicochemical and thermal properties of pyridoxine HCl using various analytical techniques such. The study plan involved dividing the pyridoxine HCl sample into two parts, in which, the first part was not given any treatment (control sample), while the second part was provided the Consciousness Energy Healing Treatment by a renowned Biofield Energy Healer, Gopal Nayak and named as the Biofield Energy Treated pyridoxine. The particle size values of the treated pyridoxine was altered by -19.51% (d10), -11.92% (d50), 2.46% (d90), and -2.44% {D(4,3)}; whereas, the surface area was significantly increased by 18.92%, compared to the control sample. The powder X-ray diffraction data showed the remarkable increase in the peak intensities and crystallite sizes of the treated pyridoxine in the range from 8.81% to 21.57% and 9.64% to 17.85%, respectively compared to the control sample. Moreover, the treated pyridoxine also showed an increase in the average crystallite size by 13.69%, compared to the control sample. The total weight loss of the treated pyridoxine was significantly reduced by 13.35% during the thermal degradation; however, the residue weight was increased by 29.48% after degradation, in comparison to the control sample. The maximum thermal degradation temperature of the treated pyridoxine corresponding to 1st and 2nd peak was altered by 4.37% and 2.24%, respectively than the control sample. The latent heat of fusion of the treated pyridoxine was significantly increased by 5.89% compared to the control sample. Hence, it was assumed that the Trivedi Effect®-Consciousness Energy Healing Treatment might form a new polymorph of pyridoxine HCl that might be helpful in designing more efficacious pharmaceutical/nutraceutical product due to its better solubility, absorption, bioavailability, and thermal stability than the untreated sample.
Highlights
Vitamin B6 occurs in the nature in the form of pyridoxine, which after absorption in the gastrointestinal tract, converted to a form of coenzyme, pyridoxal phosphate [1]
The converted form of pyridoxine i.e., pyridoxal 5-phosphate plays an important role of coenzyme in the synthesis process of amino acids, neurotransmitters such as serotonin, and norepinephrine, aminolevulinic acid, and sphingolipids, etc
Biofield Energy Treatment is a type of Energy Healing technique that may help in the treatment of various diseases and accepted by the National Center for Complementary and Alternative Medicine (NCCAM) under the CAM therapies [15, 16]
Summary
Vitamin B6 occurs in the nature in the form of pyridoxine, which after absorption in the gastrointestinal tract, converted to a form of coenzyme, pyridoxal phosphate [1]. Such conversion takes place in the liver, and further, it is involved in various metabolic processes. Pyridoxine naturally occurred in fish, poultry, grains, pork, and legumes It is available in supplement form that is used in the prevention and treatment of vitamin B6 deficiency in those people who couldn’t get enough quantity from their diets [4]. The current study has been structured with the aim to analyze the impact of the Biofield Energy Treatment on the physicochemical and thermal characteristics of pyridoxine HCl by using various analytical techniques
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