Conjunctive cavity microflora features in children with inflammatory eye adnexa pathologies

Abstract

Purpose. To evaluate microflora of the conjunctival cavity of children in different age periods without and with inflammatory diseases of the eye adnexa. Material and methods. 370 children (398 eyes) aged from 1 month to 17 years were examined. 204 clinically healthy patients (225 eyes) made up the control group. The remaining 166 children (173 eyes) were diagnosed with various inflammatory diseases: 81 children (85 eyes) had neonatal dacryocystitis; 28 (28 eyes) – acute barley and 57 (60 eyes) – chronic blepharoconjunctivitis. All children underwent conjunctival cavity smear which were cultured for flora growth and sensitivity to antibacterial drugs. Results. Most common results shows that coagulase-negative staphylococci (CNS) are detected from the conjunctival cavity, with different frequency in different age periods: infancy – 38.5%, early childhood – 70.0%, first childhood – 40.4%, second childhood – 54.3%, teenage – 53.8%, youth – 20.0%. Frequency of detection of Staphylococcus aureusincreases during inflammatory diseases, and the detection of CNS decreases. Microflora shows the greatest sensitivity tofluoroquinolones in healthy children as well as in children with inflammatory diseases. Conclusion. A diverse spectrum of microflora was revealed at the age of 4 to 15 years, as well as under 1 year old kids. There is a significant increase in the incidence of Staphylococcus aureusand a decrease in the incidence of CNS in the considered inflammatory diseases. Identified microorganisms shows the greatest sensitivity to fluoroquinolones both in healthy children and their peers with inflammatory diseases. Key words: microflora, children, inflammatory eye diseases, antibacterial drugs