Abstract
Introduction: Pterygium is a degenerative condition of subconjunctival tissues that proliferates as vascularized granulation tissue to invade the cornea. Treatment modalities may be medical or surgical. Objectives: The outcome studied in both groups in terms of operative time, postoperative symptoms, overall graft success. Material and Method: Prospective, randomized, comparative study conducted on 50 patients over a period of one year in the upgraded Department of Ophthalmology at GMC Jammu. Group, I (25 eyes) underwent attachment of conjunctival autograft by 10-0 silk suture and group II (25 eyes) attachment done without sutures. Results: Mean operating time was less without sutures (p-value = 0.0001, highly significant), the severity of Post-operative symptoms was more with suture. Graft successfully attached in both groups. Conclusion: Present study concluded that both are effective methods but autograft without sutures associated with less operating time and less post-operative discomfort in terms of severity and duration
Highlights
Pterygium is a degenerative condition of subconjunctival tissues that proliferates as vascularized granulation tissue to invade the cornea
Mean operating time was less without sutures (p-value = 0.0001, highly significant), the severity of Postoperative symptoms was more with suture
I consisted of 25 eyes who underwent attachment of conjunctival autograft by 10-0 nylon suture and in Group II (25 eyes) attachment was done without suture
Summary
Pterygium is a degenerative condition of subconjunctival tissues that proliferates as vascularized granulation tissue to invade the cornea. Objectives: The outcome studied in both groups in terms of operative time, postoperative symptoms, overall graft success. Results: Mean operating time was less without sutures (p-value = 0.0001, highly significant), the severity of Postoperative symptoms was more with suture. Conclusion: Present study concluded that both are effective methods but autograft without sutures associated with less operating time and less post-operative discomfort in terms of severity and duration. Cell mediated type-IV hypersensitivity responses [1]. Elastodysplasia and elastodystrophy [3], stem cell aplasia [4] p53 tumor suppressor gene overexpression in the epithelium of the pterygium coupled with the disruption of the normal process of apoptosis in the conjunctiva. Bowman's layer lying below the pterygium is destroyed and that is why cornea does not regain normal transparency after excision of pterygium.
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