Abstract

Congratulations to the 2016 JALA Ten!

Highlights

  • On the other end of the spectrum, Somin Eunice Lee at the University of Michigan (USA) has harnessed the power of nanotechnology to develop a gold nanoparticle–based plasmon ruler that is capable of single-molecule measurements.[2]

  • This plasmon ruler is reversible, allowing for detection of multiple events. High specificity of this reversible plasmon ruler is demonstrated with the specific detection of the matrix metalloproteinase MMP3 over its family member MMP9. Implementation of this plasmon ruler into life sciences and biomedical research should allow for greater understanding of the functions of secreted molecules in the microenvironment

  • Because of the modularity and tenability of these microporous annealed particle (MAP) gels, they should impact a wide range of regenerative medical applications, as well as drug development applications that require 3D cell culture or organ-on-a-chip methods of study

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Summary

Introduction

On the other end of the spectrum, Somin Eunice Lee at the University of Michigan (USA) has harnessed the power of nanotechnology to develop a gold nanoparticle–based plasmon ruler that is capable of single-molecule measurements.[2]. Beyond building better biosensors and more effective and cost-efficient devices, work featured this year includes improvements in automation of large-cargo intracellular delivery, as well as innovating the use of inorganic and biomaterials in medical applications.[8,9,10] This year’s honorees represent the best in research that advances translational science and technology, and we are proud to honor these researchers for their amazing work.

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