Congestive Heart Failure Patients’ Pulse Rate Progression and Time to Death at Debre Tabor Referral Hospital, Ethiopia

Alebachew Taye Belay,Setegn Bayabil Agegn,Shewayiref Geremew Gebremichael,Denekew Bitew Belay,Carol J Burns

doi:10.1155/2021/9550628

Abstract

Background. Heart failure is a progressive condition marked by worsening symptoms such as shortness of breath, coughing, exhaustion and lethargy, fluid retention with swelling of the legs and abdomen, and a reduced ability to exercise. As a result, this study aims to use a joint model application to determine the joint risk factors of longitudinal change in pulse rate and time to death of congestive heart failure patients and their association admitted to a hospital. Methods. A retrospective study was undertaken on congestive heart failure patients admitted to the Debre Tabor Referral Hospital from January 2016 to December 2019. A statistical joint modeling strategy was employed to match the repeated biomarker pulse rate and a survival outcome at the same time. A total of 271 patients with congestive heart failure were chosen. Data were analyzed with R statistical software via joineRML. Results. According to the findings, the association between longitudinal changes in pulse rate and time to death in heart failure patients is statistically significant. Sex, residence, left ventricular injection fraction, New York Heart Association class, and diabetes mellitus were all found to be significant risk factors for congestive heart failure patients’ short survival time to death. Age, sex, residence, hypertension, left ventricular injection fraction, congestive heart failure, diabetes mellitus, tuberculosis, and etiology were all significant contributors in pulse rate progression. Conclusion. The computed association parameters revealed subject-specific values. The subject-specific linear time slope of PR measurement was positively related to the hazard rate of time to death of CHF patients in the study area. To reduce the risk level of CHF, health professionals, governmental organizations, and nongovernmental organizations must promote and allocate a suitable amount of budget for the treatment of CHF patients.

Highlights

Heart failure (HF) is a potentially fatal clinical consequence characterized by structural or functional dysfunction of the pericardium, myocardium, heart valves, and metabolic imbalances in the body [1, 2]
Mortality rates for heart failure patients remain high, with 17 to 45% of deaths happening within one year of diagnosis and the majority of fatalities occurring within five years [3]. e prevalence of CHF in the adult
The goals of this study are to determine the joint risk factors of longitudinal change in pulse rate and time to death in congestive heart failure patients admitted to Debre Tabor Referral Hospital in Ethiopia, as well as their association, using a joint model application

Summary

Introduction

Heart failure (HF) is a potentially fatal clinical consequence characterized by structural or functional dysfunction of the pericardium, myocardium, heart valves, and metabolic imbalances in the body [1, 2]. According to a study conducted in 2014, the global prevalence of heart failure is estimated to be around 26 million patients [8]. This study aims to use a joint model application to determine the joint risk factors of longitudinal change in pulse rate and time to death of congestive heart failure patients and their association admitted to a hospital. The association between longitudinal changes in pulse rate and time to death in heart failure patients is statistically significant. Residence, left ventricular injection fraction, New York Heart Association class, and diabetes mellitus were all found to be significant risk factors for congestive heart failure patients’ short survival time to death. Sex, residence, hypertension, left ventricular injection fraction, congestive heart failure, diabetes mellitus, tuberculosis, and etiology were all significant contributors in pulse rate progression. To reduce the risk level of CHF, health professionals, governmental organizations, and nongovernmental organizations must promote and allocate a suitable amount of budget for the treatment of CHF patients

Objectives

Methods

Conclusion