Abstract
Rubella IgM antibody was detected 1 to 6 1/2 months postnatally in the serum of 6 infants whose mothers had had rubella during the first trimester of pregnancy; rubella virus was recovered from 5 of the infants. No rubella IgM antibody was demonstrable in the serum of 9 neonates whose mothers had had rubella during the 2 latter trimesters of pregnancy; virus was not isolated from any of them. The 6 infants who had congenital rubella infection had stationary rubella HI antibody titers and stationary or rising rubella CF antibody titers after birth. By contrast, of the 9 symptom-free babies whose mothers had had rubella late in pregnancy, rubella antibody titers were stationary in 2 of them and declining (resembling those in the control patients) in 7.
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