Abstract

Objective To investigate the diagnosis, surgical therapy of congenital pyloric atresia in neonates. Method Six congenital pyloric atresia neonates in Children′s Hospital of Nanjing Medical University were admitted, including 4 cases of complete atresia with pyloric diaphragm, 1 case of incomplete atrsia with a foraminula in the pyloric diaphragm and 1 case of pyloric atresia with solid segment. Three cases were associated with epidermolysis bullosa, multiple intestinal atresia and annular pancreas respectively. Results The main presenting symptoms were nonbilious vomiting, and 5 cases of abdominal X-ray plain film showed a large single gastric air-bubble and no gas distally. Ultrasonography and upper gastrointestinal radiography showed complete gastric outlet obstruction, and in 1 case postbulbar obstruction. Neonates with pyloric diaphragm underwent diaphragm excision and pyloroplasty, and that with solid segment did an extended pyloroplasty. The one complicating intestinal atresia was abandened surgery. Five cases were followed up, and doing well with complete recovery. Conclusion Abdominal X-ray plain film, Doppler ultrasonography and upper gastrointestinal radiography help establish the diagnosis of neonatal congenital pyloric atresia. Surgery is the therapy of choice and the prognosis is very good. Key words: Pylorus; Infant, newborn

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