Abstract

Abstract: Congenital Insensitivity to Pain with Anhidrosis (CIPA), also known as hereditary sensory and autonomic neuropathy type IV (HSAN IV), is a rare genetic disorder characterized by the inability to perceive pain and a lack of sweat (anhidrosis). This review aims to provide a comprehensive understanding of CIPA, including its clinical features, genetic basis, diagnostic challenges, and management strategies.

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