Abstract
BackgroundThis study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation.MethodsIn this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A continuous circular capsulorhexis with <6 mm diameter was employed. A capsular tension ring and HOYA yellow foldable posterior chamber intraocular lens was implanted. All patients wore color contact lenses postoperatively. Paired t test was used to compare visual acuity, intraocular pressure, and corneal endothelial changes before and after surgery.ResultsA single surgeon performed all surgeries. The best-corrected visual acuity improved from value 1.03 ± 0.27LogMAR preoperatively to value 0.78 ± 0.26LogMAR postoperatively (p = 0.000). The photophobic symptoms improved significantly after surgery. The mean corneal endothelial cell density before and after surgery was 3280 ± 473 cells/mm2 and 2669 ± 850 cells/mm2, respectively (p = 0.006). None of the patients developed corneal endothelial decompensation or secondary glaucoma after surgery.ConclusionsTreatment of congenital aniridia and coexistent cataract by phacoemulsification, posterior chamber foldable lens implantation, capsular tension ring placement was safe and effective. Use of colored contact lenses in the postoperative period can reduce photophobic symptoms in this group of patients.Trial registrationChiCTR-OOC-17011638 (retrospectively registered at 12,June,2017)
Highlights
This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation
Implantation of prosthetic iris devices during cataract surgery has been described to alleviate the photophobia symptoms induced by aniridia, serious complications such as secondary glaucoma
In this study we describe the surgical and visual outcomes of cataract surgery in cases with congenital aniridia using phacoemulsification, posterior chamber foldable lens implantation, and capsular tension ring (CTR) placement
Summary
This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. Congenital aniridia is a rare genetic eye disease due to PAX6 mutation. It is associated with neuroectodermal and mesodermal dysplasia [1, 2]. Congenital aniridia is often associated with cataract that may require surgery [1,2,3,4,5]. In this study we describe the surgical and visual outcomes of cataract surgery in cases with congenital aniridia using phacoemulsification, posterior chamber foldable lens implantation, and capsular tension ring (CTR) placement These cataracts are characterized by an early age of onset, higher risk of complications, and limited postoperative visual improvement [6,7,8,9,10].
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