Congener specific accumulation and toxic assessment of polychlorinated biphenyls in common cormorants, Phalacrocorax carbo, from Lake Biwa, Japan

Abstract

Isomer-specific accumulation of polychlorinated biphenyls (PCBs) including di-, mono- and non- ortho congeners and hepatic P-450 activities were determined in adult common cormorants from Lake Biwa, Japan. The mean total PCB levels in male and female birds were 7.2 ± 6.1 and 2.1 ± 0.74 μg g −1 wet wt, respectively, in the liver. The highly biomagnified congeners were IUPAC 126, 153, 169, 180 and 194, whereas a higher degree of biotransformation could be observed in both meta-para chlorine unsubstituted congeners in the cormorant liver. The estimated metabolic index also showed that common cormorants had higher PB-type enzyme activities than some avian and marine mammals but poor MC-type enzyme activities. The concentrations of non- ortho coplanar congeners were in the order of IUPAC 126 > IUPAC 169 > IUPAC 77 with mean values 6.1 ± 5.9, 1.3 ± 1.4 and 0.43 ± 0.26 ng g −1 wet wt, respectively. The calculated mean 2,3,7,8-TCDD toxic equivalent (TEQ) concentration in cormorants was 1.8 ± 1.7 ng g −1 wet wt and was dominated by IUPAC 118, followed by IUPAC 126. A significant increase of ethoxyresorufin- O-deethylase (EROD) and pentoxyresorufin- O-deethylase (PROD) activities was observed with estimated TEQ of PCBs in the cormorants, suggesting that the current contamination level is sufficient for altering their biochemical responses.