Abstract
Readers who were intrigued by the surprisingly general beneficial effects of measles vaccine reported by Holt et al1 may be interested to know that a precedent exists for such a finding. A series of articles by Black, Fox, Elveback, and co-workers2-6 deserve greater attention. In three independent and classic studies, they documented that preschool children with a history of measles infection had lower cognitive test scores than measles-susceptible children. This effect occurred despite use of approximately six covariates for adjustment.
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