Abstract

Antibody-based therapeutics are a fast-growing sector in the pharmaceutical industry. One large contributor to the high cost associated with development of new antibody therapeutics is the separation and purification process, which is currently iterative and empirical. More information about how antibodies interact with stationary phases would be helpful in improving the process. I will discuss our recent efforts to track single, fluorescently labeled antibodies as they interact with an ion-exchange stationary phase.

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