Conformation-sensitive infrared bands of uridine-5′-monophosphate

Abstract

Infrared spectra are presented for six compounds containing ribose residues with various conformations. The assignments are based chiefly on comparison of the vibrational data observed for these compounds with those for uracil and d-ribose-5-phosphate and on a previous normal coordinate calculation. A spectral feature in the 1300−1260 cm −1 region seems to be sensitive to the ribofuranose conformation, and the usefulness of these structure-spectrum correlations in the conformation studies of polynucleotides is also discussed.