Conformation of aromatic disulphides: the molecular structure of Ellman's reagent

Abstract

The conformation of an aromatic disulphide linkage is best described by two torsion angles: the one involving the C–S–S–C atoms (usually near 90°) and that relating the orientation of the S–S bond to the plane of the phenyl ring (either ca. 0° or ca. 90°).