Confocal Single-Pixel Imaging

Abstract

Obtaining depth-selective images requires gating procedures such as spatial, nonlinear, or coherence gating to differentiate light originating from different depths of the volume of interest. Nonlinear gating requires pulsed excitation sources and excitation probes, limiting easy usage. Coherence gating also requires broadband sources and interferometry requiring specialized stable setups. Spatial gating can be used both for fluorescence and reflection geometry and various light sources and thus has the least requirements on hardware, but still requires the use of a pinhole which makes it difficult to use for photography or widefield imaging schemes. Here, we demonstrate that we can utilize a single digital micromirror device (DMD) to simultaneously function as a dynamic illumination modulator and automatically synchronized dynamic pinhole array to obtain depth-sectioned widefield images. Utilizing the multiplexed measurement advantage of single-pixel imaging, we show that the depth and ballistic light gating of the confocal single pixel imaging scheme can be utilized to obtain images through glare and multiple scattering where conventional widefield imaging fails to recover clear images due to saturation or random scattered noise.