Abstract
The purpose of the current paper is to describe the functioning protocol of a femoral heads bone bank in a specialised tertiary orthopaedic hospital in Bucharest and the results of its activity between January 2011 and December 2016. Since the initiation of the femoral head bone bank in 2011, we selected and tested 761 donors of femoral heads. Out of them, we implanted 435 grafts to a total of 242 recipient patients. We performed a thorough donor screening process, which resulted in a significant proportion of femoral head allografts discarded, mainly due to a positive hepatitis B or/and C viruses test or a positive result of the bacterial culture from the bone graft (in 3% of the grafts); the offending micro-organism was a Methicillin-Sensible Staphylococcus spp. Our bone bank may serve as a framework for developing similar structures by other hospitals in our country or elsewhere.
Highlights
Reconstruction of bone defects is possible by using whether autologous or allogenic bone graft
Bone grafts are necessary for reconstructing significant bone defects that may result from trauma, extensive bone tumour resection or after bone infection [3, 4]; in spinal fusion procedures [5], in revision total joint arthroplasty [6] or revision anterior cruciate ligament reconstruction [7]
The purpose of the current paper is to describe the functioning protocol of a femoral heads bone bank in a specialised tertiary orthopaedic hospital in Bucharest, organised under the national and European transplant regulations, and the results of its activity between January 2011 and December 2016, as an experience that may serve as a framework for developing similar structures by other hospitals
Summary
Reconstruction of bone defects is possible by using whether autologous or allogenic bone graft. Autologous bone graft may be considered superior due to its concomitant osteoinductive and osteoconductive properties, its reduced availability and associated donor site morbidity may limit its use [1, 2, 3]. Allogenic bone grafts may be available in larger quantities due to bone banks. This type of graft has only osteoconductive properties, being only a frame for the newly formed bone. An allogenic bone graft can be obtained from banks that store tissues resulted from deceased patients [8, 9] or banks that store femoral heads from selected live patients who underwent a hip arthroplasty procedure. Besides the reduction in financial costs, these local bone banks offer the advantage of easy access to the graft, an issue of the highest importance especially for secondary and tertiary orthopaedic centres with numerous procedures for which bone graft material is mandatory
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