Confidence estimation based on data from independent studies.

Abstract

The problem of finding confidence intervals based on data from several independent studies or experiments is considered. A general method of finding confidence intervals by inverting a combined test is proposed. The combined tests considered are the Fisher test, the weighted inverse normal test, the inverse chi-square test and the inverse Cauchy test. The method is illustrated for finding confidence intervals for a common mean of several normal populations, common correlation coefficient of several bivariate normal populations, common coefficient of variation, common mean of several lognormal populations, and for a common mean of several gamma populations. For each case, the confidence intervals based on the combined tests are compared with the other available approximate confidence intervals with respect to coverage probability and precision. R functions to compute all confidence intervals are provided in a supplementary file. The methods are illustrated using several practical examples.