Abstract
Background: The aim of this study was to evaluate the diagnostic capacity of Cone-Beam computed tomography (CT)-guided transthoracic percutaneous biopsies on lung lesions in our setting and to detect risk factors for possible complications. Methods: Retrospective study of 98 biopsies in 94 patients, performed between May 2017 and January 2020. To obtain them, a 17G coaxial puncture system and a Siemens Artis Zee Floor vc21 archwire were used. Descriptive data of the patients, their position at the time of puncture, location and size of the lesions, number of cylinders extracted, and complications were recorded. Additionally, the fluoroscopy time used in each case, the doses/area and the estimated total doses received by the patients were recorded. Results: Technical success was 96.8%. A total of 87 (92.5%) malignant lesions and 3 (3.1%) benign lesions were diagnosed. The sensitivity was 91.5% and the specificity was 100%. We registered three technical failures and three false negatives initially. Complications included 38 (38.8%) pneumothorax and 2 (2%) hemoptysis cases. Fluoroscopy time used in each case was 4.99 min and the product of the dose area is 11,722.4 microGy/m2. Conclusion: The transthoracic biopsy performed with Cone-Beam CT is accurate and safe in expert hands for the diagnosis of lung lesions. Complications are rare and the radiation dose used was not excessive.
Highlights
Percutaneous transthoracic biopsy (PTB) is a well-established and frequently used procedure for the diagnosis of lung nodules, regardless of their size [1,2,3]
PTB can be performed using fluoroscopic or ultrasound guidance, techniques guided by computed tomography (CT) and CT fluoroscopy have become generalized for the diagnosis of small lung lesions [2,3]
Recently, Cone-Beam CT (CBCT) systems consisting of a C-arc, X-ray tube, and flat-panel-type detector have been introduced to the field of interventional radiology [7,8,9,10,11]
Summary
Percutaneous transthoracic biopsy (PTB) is a well-established and frequently used procedure for the diagnosis of lung nodules, regardless of their size [1,2,3]. PTB can be performed using fluoroscopic or ultrasound guidance, techniques guided by computed tomography (CT) and CT fluoroscopy have become generalized for the diagnosis of small lung lesions [2,3] Both are precise and safe techniques [1,2,3]. Recently, Cone-Beam CT (CBCT) systems consisting of a C-arc, X-ray tube, and flat-panel-type detector have been introduced to the field of interventional radiology [7,8,9,10,11] These systems offer great flexibility to orient the detector around the patient, provide CT images that can be reconstructed three-dimensionally, and allow real-time fluoroscopy. Complications are rare and the radiation dose used was not excessive
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