Abstract
Background: Oral squamous cell carcinoma which occurs closely to the mandible has a tendency to invade mandible. An accurate preoperative evaluation of mandibular invasion is important for optimum treatment planning. Aim of this study is to determine the accuracy of CBCT in detection of mandibular invasion in oral squamous cell carcinoma.
 Study design: In this prospective observational study 35 patients of histologically proven squamous cell carcinoma which was close proximity to the mandible were selected. The results of preoperative CBCT scan of mandible were compared with that of post operative histopathology of bone and thus sensitivity, specificity, negative predictive value, positive predictive value were calculated.
 Results: Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CBCT were 96%, 90.90%, 96%, 90.90%, 97.14% respectively (Chi squared with Yates correction equals 21.844 with 1 degrees of freedom, p value < o.oooo1).
 Conclusion: Cone beam computed tomography is a sensitive test and has an acceptable range of specificity.
 Update Dent. Coll. j: 2018; 8 (2): 18-22
Highlights
Oral Squamous Cell Carcinoma (OSCC) which is in close proximity to the mandible has a tendency to invade it
Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of cone beam computed tomography (CBCT) were 96%, 90.90%, 96%, 90.90%, 97.14% respectively (Chi squared with Yates correction equals 21.844 with 1 degrees of freedom, p value < o.oooo1)
Among the positive invasion of bone which was confirmed by histopathology 96% were detected by CBCT scan
Summary
Oral Squamous Cell Carcinoma (OSCC) which is in close proximity to the mandible has a tendency to invade it. According to different studies the prevalence of mandibular bone involvement ranges from 12%-56% 1. The incidence of mandibular invasion in oral cancer ranges from 12 to 56% according to various studies[2, 3]. It is understandable that for better quality of life, it is possible to preserve mandible as much as possible without compromising the local control. Oral squamous cell carcinoma which occurs closely to the mandible has a tendency to invade mandible. Aim of this study is to determine the accuracy of CBCT in detection of mandibular invasion in oral squamous cell carcinoma
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