Conditional Cancer Survival of the Corpus Uterine in the USA

Abstract

Purpose To identify relative survival probabilities for corpus uterine cancer patients accounting for time already survived, as well as age, race, ethnicity, marital status, tumor stage, and tumor grade at diagnosis. Methods Analyses are based on 78,147 women diagnosed with corpus uterine cancer during 2000-2008 and followed through 2013, using data from the National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) program. Results Age, race, marital status, tumor stage, and tumor grade, but not ethnicity, significantly impacted relative cancer survival rates of the corpus uterine. Improvement in 5-year relative survival, when conditioned on 1-5 years already survived, occurs in each stage category, more so in later staged cases. The effect of age, race, marital status, and tumor grade on 5-year relative survival, after conditioning on years ( 1 - 2 - 3 - 4 - 5 ) already survived, varied by stage at diagnosis. For example, poorer prognosis with older age was only observed for regional and distant staged cases, but being married had a greater beneficial impact in regional and distant staged cases. The difference in 5-year relative survival rates diminished for age, race, marital status, tumor stage and grade when conditioned on years ( 1 - 2 - 3 - 4 - 5 ) already survived. The greatest improvement in 5-year conditional relative survival was in patients 70 years or older, Blacks, singles, later staged tumors, and higher grade tumors. Conclusions Reporting cancer survival estimates according to time already survived and demographic subgroups provide health-care providers and patients with more instructive prognostic information.