CONDITION OF CENTRAL HEMODYNAMICS IN NEWBORNS WITH CONVULSIONS

Abstract

Summary.Introduction. The article is devoted to topical issue of the modern neonatology - to the condition of the central hemodynamics of newborns. The regulation of heart and blood vessels activity is impaired as a result of hypoxia. It affects on energy metabolism of myocardium and reduces contractile capacity of myocardium with arrhythmias and conduction abnormalities.Materials and Methods. The examination of 54 infants in the early neonatal period (the analysis of the obstetric anamnesis, physical examination, ECG, Doppler echocardiography, amplitude-integrated EEG) was conducted.Results and Discussion. Convulsions were found in 21 (38.9%) children. Subclinical convulsions with convulsive patterns according to amplitude-integrated electroencephalography were 12 (22.2%) infants. 66.7% of children with clinical convulsions had hypokinetic type of central hemodynamics, 22.2% - normokinetic, 11.1% - hyperkinetic. A similar division was in the group of children with subclinical convulsions: 58.3% - hypokinetic type, 25% - normokinetic, 16.7% - hyperkinetic. 33 babies without convulsions had equal distribution of variants of central hemodynamics: hypokinetic - 39.4% normokinetic - 30.3%, hyperkinetic - 30.3%.Conclusions. At examination of newborns with a convulsive syndrome by means of Doppler echocardiography it wasn’t revealed significant differences of distribution by variants of the central hemodynamics in children with clinical and subclinical convulsions. Neonates with a convulsive syndrome have authentically lower indicator of a systolic index, than babies without convulsions (p <0.05), that testifies about the prevalence in them prognostically unfavorable hypokinetic type of the central hemodynamics. According to our research 61,9% of newborns with a convulsive syndrome have it.