Condensed Tannins Improved Immune Functions and Reduced Environmental Pollution of Captive Sichuan Black Goat Kids Under Cadmium Toxicity

Abstract

To investigate the effects of condensed tannins (CT) on immune functions and nitrogen (N) emissions of captive Sichuan black goat kids under cadmium (Cd) toxicity, a total of 18 Sichuan black goat kids (2months old, 9.6 ± 1.2kg) were randomly used in this 30-day trial. The dietary treatments were (1) CON group, basic diet; (2) Cd group, basic diet + oral 10mg Cd/kg·BW; and (3) CT group, Cd group + 400mg/kg CT. Oral Cd supplementation significantly decreased the Cu and Fe contents in serums and livers of captive Sichuan black goat kids (P < 0.05), but adding CT in the Cd group increased the Fe and Mo contents and decreased the Cd content in serums and livers (P < 0.05). Additional CT supplementation in the Cd group extremely increased the activities of serum SOD, GSH-Px, and CAT (P < 0.05), and greatly decreased the serum MDA content (P < 0.05). The CT supplementation in the Cd group also extremely increased the concentrations of serum IgG, IgM, and IgA (P < 0.05), and greatly decreased the contents of IL-6, IL-1β, and TNF-α in serums (P < 0.05). Adding CT in the Cd group significantly increased the apparent digestibility of CP and EE and decreased the urinary nitrogen (UN) content (P < 0.05, Table 7). In conclusion, the application of additional CT improved antioxidant capacities and immune functions of captive black goats under Cd toxicity, then reduced the oxidative stress and toxic damage of Cd contamination. CT also improved the N digestibility and reduced the N emission, which was helpful to reduce environmental pollution.