Abstract

This was a case-control cohort study that investigated the risk of bleeding in older adults on chronic warfarin with concurrent use of any of six commonly prescribed antibiotic classes: azole antifungals, macrolides, quinolones, cotrimoxazole, penicillins, or cephalosporins. The study used data from the Medicare Part D prescription drug program to identify 38,762 adults aged > 65 years on chronic warfarin and followed them for a study period of 1 year (2008), and recorded cases of bleeding events requiring hospitalization and their association with antibiotic exposure, divided by recency of exposure as: 0–15 days, 16–60 days, or > 60 days.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.