Abstract
BackgroundColonic lymphoma is an uncommon presentation of extranodal lymphoma. Colonic mucosa-associated lymphoid tissue lymphoma is a different entity from gastric mucosa-associated lymphoid tissue lymphoma, and very rare. The presentation and management of colonic mucosa-associated lymphoid tissue are highly variable in the literature.Case presentationWe report the case of a 59-year-old Taiwanese man who underwent a colonoscopy after a positive test for fecal occult blood. His past history included hypertension and hyperthyroidism. The colonoscopy revealed an adenomatous polyp and mucosa-associated lymphoid tissue lymphoma. We successfully performed a polypectomy and endoscopic mucosal resection. The lymphoma was staged according to the Ann Arbor system modified by Musshoff as E-I. Our patient showed no lymphoma recurrence over a 3-year follow-up.ConclusionsEndoscopic mucosal resection for colonic mucosa-associated lymphoid tissue lymphoma without disseminated disease may be feasible. We successfully used colonoscopic treatment without adjuvant therapy to treat early-stage pathogen-free colonic mucosa-associated lymphoid tissue lymphoma.
Highlights
Colonic lymphoma is an uncommon presentation of extranodal lymphoma
Colon lymphomas account for 15–20 % of gastrointestinal lymphomas [1], 1.4 % of all nonHodgkin’s lymphomas [3], and 1 % of all colorectal malignancies [4]
An immunohistochemical study demonstrated that the larger polyp was positive for CD20, CD5, and Bcl-2, and negative for CD10 and cyclin D1 (Fig. 2b). These results supported our diagnosis of extranodal marginal zone lymphoma of Mucosa-associated lymphoid tissue (MALT) type
Summary
Endoscopic mucosal resection for colonic mucosa-associated lymphoid tissue lymphoma without disseminated disease may be feasible.
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