Abstract
Concurrent Administration of Curcumin Mitigates Arsenic - and Chlorpyrifos - induced Apoptosis in Rat Thymocytes
Highlights
It is becoming increasingly evident that environmental exposures in humans and animals are not just limited to single chemicals
Arsenic and chlorpyrifos in combination potentiated the induction of apoptosis than their alone effect, concurrent administration of curcumin considerably inhibited the induction of apoptosis by scavenging free radicals
In West Bengal, more than 6 million people in nine districts are endemically exposed to inorganic arsenic by drinking heavily contaminated groundwater from hand–pumped tube–wells (Chowdhury et al, 2001) while Ballia district of eastern Uttar Pradesh (GOI, 2011) and arsenic contamination in Ganga–Meghna– Brahmaputra (GMB) plain (Chakraborti et al, 2010) are heavily contaminated with arsenic
Summary
It is becoming increasingly evident that environmental exposures in humans and animals are not just limited to single chemicals. Arsenic and chlorpyrifos in combination potentiated the induction of apoptosis than their alone effect, concurrent administration of curcumin considerably inhibited the induction of apoptosis by scavenging free radicals.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.