Abstract
We report a case of coexisting urothelial cancer and renal tuberculosis in the same kidney. The patient is a 72-year-old female with a remote history of treated pulmonary tuberculosis who presented with haematuria, initial investigation of which elucidated no definitive cause. Almost 1 year later, a diagnosis of metastatic urinary tract cancer was made. The patient received chemotherapy for advanced collecting duct type renal cell carcinoma, based on histological features of renal biopsy. Subsequent confirmatory immunostains however led to a revised diagnosis of urothelial cancer, necessitating a change in chemotherapy regimen. A diagnosis of ipsilateral renal tuberculosis was made based on TB-PCR testing of renal biopsy tissue and anti-TB therapy was coadministered with chemotherapy. The patient died 9 months after diagnosis of metastatic urothelial cancer.
Highlights
The occurrence of tuberculosis and urothelial cancer in the same kidney is rare
We report the case of a patient investigated for haematuria and found to have coexisting renal tuberculosis and urothelial cancer
Renal tuberculosis is a well-known complication of pulmonary TB with an 8–10% risk of genitourinary TB developing in a patient with known pulmonary tuberculosis [2]
Summary
The occurrence of tuberculosis and urothelial cancer in the same kidney is rare. Only one previous case has been reported in the English language literature [1]. We report the case of a patient investigated for haematuria and found to have coexisting renal tuberculosis and urothelial cancer
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